Atheromatous Plaque

Atherosclerosis is a disease in which the inside of an artery narrows due to the build-up of plaque. Initially, there are generally no symptoms. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which arteries are affected. Symptoms, if they occur, generally do not begin until middle age.

Risk factors

Diabetes, Dyslipidaemia, Tobacco smoking, Trans fat, Abdominal obesity, Insulin resistance, Hypertension, etc.

Mechanism

Atherogenesis is the developmental process of atheromatous plaques. It is characterized by a remodeling of arteries leading to subendothelial accumulation of fatty substances called plaques. The buildup of an atheromatous plaque is a slow process, developed over a period of several years through a complex series of cellular events occurring within the arterial wall and in response to a variety of local vascular circulating factors

Diagnosis

Areas of severe narrowing, stenosis, detectable by angiography, and to a lesser extent "stress testing" have long been the focus of human diagnostic techniques for cardiovascular disease, in general. However, these methods focus on detecting only severe narrowing, not the underlying atherosclerosis disease.

Prevention

Diet, Exercise, Treatment, Statins, Surgery, Others

Best Regards

Senior Journal Coordinator

Editorial office

Laura Gray